Most biorefinery processes have relied on the use of biomass as a raw material for the production of chemicals and materials. Even though the use of CO2 as a carbon source in biorefineries is desirable, it has not been possible to make common microbial strains such as E. coli grow on CO2.
Now, a metabolic engineering research group at KAIST has developed a strategy to grow an E. coli strain to higher cell density solely on CO2 and formic acid. Formic acid is a one carbon carboxylic acid, and can be easily produced from CO2 using a variety of methods. Since it is easier to store and transport than CO2, formic acid can be considered a good liquid-form alternative of CO2.
With support from the C1 Gas Refinery R&D Center and the Ministry of Science and ICT, a research team led