Results suggest retrieval of cellular powerplants via an energy feedback loop sustains communication — ScienceDaily

Our thoughts, feelings, and movements are controlled by billions of neurons talking to each other at trillions of specialized communication points called synapses. In an in-depth study of neurons grown in laboratory petri dishes, National Institutes of Health researchers discovered how the chattiest of some synapses find the energy to support intense conversations thought to underlie learning and memory. Their results, published in Nature Metabolism, suggest that a series of chemical reactions control a feedback loop that senses the need for more energy and replenishes it by recruiting cellular powerplants, called mitochondria, to the synapses. The experiments were performed by researchers in a lab led by Zu-Hang Sheng, Ph.D., at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS).

The team studied synapses that use the neurotransmitter glutamate to communicate. Communication happens when a packet of glutamate is released from presynaptic boutons which are tiny protrusions that stick

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How feedback platforms can improve product quality by 20% in 30 days (VB Live)

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“Companies trying to grow, trying to increase engagement and retention, can’t do that if they don’t have actionable intelligence around quality issues,” says Anthony Heckman, head of growth at unitQ.

Companies compete around a variety of vectors, he explains. In the content arena, it’s incredibly easy for companies to copy functionality that works. Snapchat grows successful and Instagram launches Live. TikTok gets big, and Instagram launches Reels. A company can compete on price, but you don’t necessarily want to be the lowest cost provider in your industry. That means product quality is key.

“We see, across the board, that category-leading companies, without question, are winning on this

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