Through a simple process of heating and cooling, New York University researchers have created a new crystal form of deltamethrin — a common insecticide used to control malaria — resulting in an insecticide that is up to 12 times more effective against mosquitoes than the existing form.
The findings, published in the journal Proceedings of the National Academy of Sciences (PNAS), may provide a much-needed and affordable insecticide alternative in the face of growing resistance among mosquitoes.
“The use of more active crystal forms of insecticides is a simple and powerful strategy for improving commercially available compounds for malaria control, circumventing the need for developing new products in the ongoing fight against mosquito-borne diseases,” said Bart Kahr, professor of chemistry at NYU and one of the study’s senior authors.
“Improvements in malaria control are needed as urgently as ever during the global COVID-19 crisis,” added Kahr. “The number of