Immune T cells swarm to tumours by following a chemical gradient left by other cancer-killing T cells — ScienceDaily

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

The discovery of this swarming behaviour, and the chemical attractants that immune cells use to direct swarms towards tumours, could one day help scientists develop new cancer therapies that boost the immune system. This is particularly important for solid tumours, which so far have been less responsive to current immunotherapies than cancers affecting blood cells.

“Scientists have previously thought that cancer-killing T cells identified tumours by randomly searching for them or by following the chemical trails laid by other intermediary immune cells,” says lead author Jorge Luis Galeano Niño, a PhD graduate at UNSW Sydney. “We wanted to investigate this further to see if it’s true, or whether T cells locate tumours via another mechanism.”

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Huawei’s Rivals Are Already Filling A $27 Billion Hole Left By US Sanctions

After more US sanctions have all-but-crippled the future of Huawei’s global networks business — and its efforts to become the dominant 5G provider — dollar signs are already materializing for its rivals.

At the crux of Huawei’s withdrawal is an annual $27 billion opportunity for its competitors — including Nokia, Ericsson and Samsung — to become the go-to providers of 5G and other telecommunication services to domestic carriers, says Ryan Koontz, an analyst at Rosenblatt Securities. “It’s a massive economic transition,” says Koontz. “It’s relatively urgent for these carriers to make the change.” 

The multi-billion dollar market opportunity, which hinges on Huawei’s sales figures for the year ended September, will not evaporate overnight, Koontz says, but will likely be absorbed over the next three to four years. 

Because

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Apple’s New 5G IPhones May Be Left on the Shelf

(Bloomberg Opinion) — Apple Inc. has been in the spotlight lately, between antitrust scrutiny of its mobile operating system and the legal battle it’s waging with Fortnite-maker Epic Games Inc. over its App Store. Those developments pale, however, in comparison to the company’s main event next week: the unveiling of its latest iPhones.

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For all the talk about Apple’s shift to services and subscriptions, the tech giant’s business is still dependent on its core hardware products, so Tuesday’s presentation will be a must-see for investors. There could be a problem this year, though. The lineup’s most vaunted feature — fifth-generation wireless capability — may not be ready for prime time. 

The Cupertino, California-based company is expected to unveil four new iPhone models with 5G capabilities as well as a different physical design and a wider choice of screen sizes, Bloomberg News reported last month. Apple is already touting 

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Valve’s Last Stand Update Could Be Hinting About ‘Left 4 Dead 3’

KEY POINTS

  • Valve recently released The Last Stand DLC for “Left 4 Dead 2
  • The new campaign introduced new weapons, rolled out bug fixes and featured characters
  • The Last Stand DLC could indicate that Valve is open to developing “Left 4 Dead 3”

Valve rolled out The Last Stand DLC campaign for “Left 4 Dead 2,” ending an almost a decade of update drought for the successful horror title, but a new report believes that the studio’s recent activities could be hinting that “Left 4 Dead 3” could be on the way.

Gamerant speculated that Valve’s recent push towards the new content of “Left 4 Dead” and “Half-Life” could indicate that a sequel of the horror title could finally be on the way. While many believed that Valve is no longer actively developing games, the release of “Half-Life: Alyx” and The Last Stand update prove otherwise.

The publication also thinks

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How Blue and White is both left and right

The party formed to represent the Israeli center has been going to extremes.On one side there are the loud voices from the Left side of the party, but there are voices on the Center-Right side as well.On the Center-Left, there is Tourism Minister Asaf Zamir, whose resignation takes effect on Monday; Science and Technology Minister Izhar Shay, who almost quit last week; and MKs Miki Haimovich and Ram Shefa, who voted against limits on political demonstrations in the Knesset.Haimovich made news on Sunday, when she said there is a group that is growing in Blue and White that is interested in breaking up the partnership with Likud. Other MKs talked about starting to vote more independently.But even if they are growing, they are still the minority in the party. The overwhelming majority of the MKs in the Blue and White-Derech Eretz-Labor bloc prefers staying the course and continuing the strategy
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A leading Silicon Valley exec says Big Tech prioritized lower costs over employees’ wellbeing, and it’s created a feudalist system where workers are left to fend for themselves



a man riding on the back of a truck: Sean Gallup/Getty Images


© Sean Gallup/Getty Images
Sean Gallup/Getty Images

  • Maëlle Gavet is a leading Silicon Valley executive, entrepreneur, investor, and most recently, the chief operating officer at real estate platform Compass.
  • The following is an excerpt from her first book, “Trampled by Unicorns: Big Tech’s Empathy Problem and How to Fix It.”
  • In it, she examines how Big Tech’s failure to empathize with customers and workers has led to “digital era’s equivalent of feudalism.”
  • In her in-depth critique of the world’s largest tech corporations — including Amazon, Uber, and Google — she crafts an earnest call to action for industry leaders, board members, employees, and consumers to get tech back on track. 
  • Visit Business Insider’s homepage for more stories.

Right now the jury is still out on whether the tech economy is ultimately a job creator or a job destroyer. As with many of the points in this book, that topic is

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BrainChip Holdings 1,500% Rise Left CEO Louis DiNardo Dumbfounded

A meteoric rally in an Australian penny stock is fast unraveling after confounding not just market watchers but also the company’s CEO.

BrainChip Holdings Ltd., an artificial intelligence-focused startup whose flagship product is yet to be made widely available for commercial use, saw its 2020 gains propel to 1,500% earlier this month. While concerns about overheating have seen the stock getting hammered since, its 762% advance year-to-date still makes for one of the best performances among technology names in Asia Pacific, according to data compiled by Bloomberg.

“I was surprised about the peak” Louis DiNardo, BrainChip’s chief executive officer, said in an interview. “Shares were overbought for a company that’s just introducing its product.”

BrainChip shares have tumbled after hitting a record earlier in the month

BrainChip is one in a long list of global technology stocks that have surged this year as the pandemic put investor spotlight on companies focused on technological innovation. BrainChip is developing a processor, Akida, that can

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Indian start-up ShareChat is one of many looking to fill the vacuum left by TikTok ban

  • ShareChat, a Twitter-backed Indian social media platform that caters to users in 15 regional languages, launched a short-video sharing app just days after New Delhi banned TikTok.
  • The app, Moj, now has more than 80 million monthly active users who spend on average 34 minutes on the platform, the company said. 
  • The TikTok ban left a vacuum that local start-ups are moving in to fill. 



a close up of a person wearing a mask: A girl wearing a protective mask depicting the TikTok logo poses for a picture in Mumbai, India, July 1, 2020.


© Provided by CNBC
A girl wearing a protective mask depicting the TikTok logo poses for a picture in Mumbai, India, July 1, 2020.

SINGAPORE — India’s ban of the popular short-video sharing app TikTok has left a vacuum that local start-ups are moving in to fill. 

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One of those start-ups is ShareChat, a Twitter-backed Indian social media platform that caters to users in 15 regional languages.

Citing national security concerns, New Delhi announced the ban on TikTok, which is owned by Beijing-based

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After 40 Years, Updated Pain Definition Aims To Include Those Once Left Out

It’s not uncommon for people with chronic pain but no clear injury to deal with doubting physicians.

Katie Clark, a retired middle school English Language Arts teacher in Michigan with fibromyalgia, said she has been lucky with her doctors. Fibromyalgia causes chronic pain that doctors think arises from amplified pain signals in the brain and spinal cord.

“I’ve been fortunate to have doctors that mostly believe the pain I feel is real,” she said. But even then, “They don’t fully understand that it affects you emotionally, physically, your energy level, your ability to think straight. That is difficult to communicate to doctors.”

In the past, healthcare providers have ascribed to a narrow definition of pain, viewing

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