N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients according to a new University of California, Irvine-led study.
Published in the Journal of Biological Chemistry, the study also demonstrates that in mice, delivering N-acetylglucosamine orally to lactating mothers drove primary myelination in their nursing offspring. N-acetylglucosamine is a simple sugar that is metabolically attached to proteins at the cell surface to control cellular function.
“We found that N-acetylglucosamine activates myelin stem cells to promote primary myelination and myelin repair,” said Michael Demetriou, MD, PhD, FRCP(C), professor of neurology, microbiology and molecular genetics at UCI School of Medicine and leader of the study. “Our data raises the intriguing possibility that N-acetylglucosamine may be a simple therapy to promote myelin repair in multiple sclerosis patients.”
Anyone wondering how to speed up your home internet without dropping a ton of cash on an overpriced mesh Wi-Fi system will be happy to hear that it’s much easier and less expensive than you think.
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Tim Cook was a guest at The Atlantic Festival, where he sat for a virtual interview with Editor-in-Chief, Jeffrey Goldberg. During their conversation Cook talked about everything from climate change, to how Apple is handling the pandemic, both from the perspective of working remotely, as well as what the company is doing to help.
It was at the end of the interview, however, when things shifted to something more personal. Goldberg asked Cook first about whether he had plans to leave (he says he doesn’t), and then what impact Apple’s $2 trillion market cap had on the company (it sits at just under that as of today’s date).
We’ll get to Cook’s response in a moment, because I think it says a lot about Apple and what has long drawn its most loyal fans to the company. That’s an important thing right now as the company has faced criticism over