The raging lung inflammation that can contribute to death from the flu can be stopped in its tracks by a drug derived from a naturally occurring human protein, a new animal study suggests.
In mouse studies, all untreated animals given a lethal dose of influenza died within days. All but one of the infected mice treated with the experimental therapy not only survived, but remained energetic and kept weight on — despite having high levels of the flu virus in their lungs.
The experimental treatment is a heavy dose of MG53, part of a family of proteins that plays an essential role in cell membrane repair. Already identified as a potential therapy for conditions ranging from Alzheimer’s disease to persistent skin wounds, MG53 was found in this study to prevent death from a lethal flu infection by blocking excessive inflammation — without having any effect on the virus itself.
Most entrepreneurs wish they were better at managing their time. There are only eight hours in a standard work day, but it feels like you have 20 hours worth of tasks to do every day.
There are many legitimate solutions to this dilemma. One of the most valuable strategies is learning to delegate effectively to reduce your total workload. You can also automate certain tasks so you no longer have to actively manage them.
A new class action lawsuit alleges that Apple enjoys monopoly power in the iOS mobile gaming marketplace, and exhibits anticompetitive behavior to keep it that way.
The complaint, lodged in the U.S. District Court for the Northern District of California, claims that Apple has “unlawfully [foreclosed] competition” through “persistent, pervasive, and secretive” misconduct.
New Jersey man John Pistacchio, the plaintiff in the case, claims to be paying “supracompetitive prices” for Apple Arcade as a result of the company’s alleged anticompetitive behavior.
More specifically, the lawsuit suggests that Apple exerts monopoly power over the iOS App Store by requiring developers to follow its app guidelines and by prohibiting third-party app stores. It adds that developers and app publishers are “powerless to constrain” Apple’s conduct by refusing to publish apps on iOS.
“No developer or group of developers have sufficient power to entice enough iOs users to leave iOS, such that
A US judge has ruled that a ban on TikTok ordered by the Trump administration will not go into effect as planned today (via CNBC). The decision means that the app will remain available to Americans for new downloads on Android and iOS stores. However, the reprieve will be temporary while the court determines the legality of the ban and whether it poses a risk to national security, as the White House has charged.
Shortly before the ban was set to take effect, US district judge Carl Nichols granted the preliminary injunction sought by TikTok owner ByteDance. However, the court declined to halt additional restrictions set to take effect on November 12th that would have effectively killed the app in the US.
“The government will comply with the injunction and has taken immediate steps to do so, but intends to vigorously defend the [executive order] and the Secretary’s implementation
A mix of ultrapotent antibodies from recovered COVID-19 patients has been shown to recognize and lock down the infection machinery of the pandemic coronavirus and keep it from entering cells. Each of the antibody types performs these overlapping tasks slightly differently.
Low doses of these antibodies, individually or as a cocktail, were also shown to protect hamsters from infection when exposed to the coronavirus by preventing it from replicating in their lungs.
An advantage of such cocktails is that they might also prevent the natural mutant forms of the virus that arose during this pandemic to escape treatment. As some variants in the infection machinery have already been discovered during the coronavirus pandemic, using a mix of antibodies allows for neutralization of a broad spectrum of such viral variants.
In addition to preventing virus entry into host cells, the presence of the antibodies also seems to set off the infection-fighting