EXCEL, SYNTAXES Analyses Spotlight Periprocedural MI Controversy

Investigators from the EXCEL trial have doubled down on the July publication of their study’s outcomes based on an alternative definition of myocardial infarction (MI) resulting from coronary revascularization, a key part of the controversy that has dogged EXCEL for a year or more.

The latest, more granular EXCEL analysis pits periprocedural MI (PMI), as defined in the trial’s protocol, against PMI according to the more stringent third Universal Definition Of Myocardial Infarction (UDMI). The stakes for EXCEL’s message are high because PMI is part of the composite primary end point.

The new analysis concludes with a preference for interpreting EXCEL — which compared percutaneous coronary revascularization (PCI) and coronary artery bypass (CABG) surgery in patients with left-main coronary artery disease (LMCAD) — using the protocol-specified PMI definition, which was based solely on levels of CK-MB (and sometimes troponin), rather than the UDMI. That alternative definition adds clinical signs, electrocardiography

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3 ways gaming phones excel: You don’t get this in an iPhone or Galaxy

“Why are gaming phones still a thing?” That’s what my colleague Michael Simon pondered after the recent releases of the Asus ROG Phone 3 and Lenovo Legion Phone Duel, and it’s a fair question to ask.

When the Razer Phone created the “gaming phone” market in 2017, it rolled out with unique features rarely—if ever—seen in smartphones: a high refresh rate screen, binned processors, copper vapor chambers, and in-your-face “gamer” aesthetics. But in the years since, many of those “gaming” features have trickled down to mainstream phones like the Samsung Galaxy and various OnePlus models. Again: Why are gaming phones still a thing?

Asus ROG Phone 3 Adam Patrick Murray/IDG

Asus ROG Phone 3 and it’s ROG UI

Don’t be fooled: Despite the mainstream adoption of some of their features, these fire-breathing, enthusiast-focused devices continue to innovate. As someone who covered many of the most popular gaming phones, there are three key features (beyond

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