Pre-clinical study suggests virus does not stay in the lungs but spreads throughout the mother’s body — ScienceDaily

New research helps explain why flu can lead to life-threatening complications during pregnancy, suggesting the virus does not stay in the lungs but spreads throughout the mother’s body.

The pre-clinical study has overturned current scientific thinking on the reasons why flu infections affect pregnant women and their babies so severely.

The findings could also help researchers working to understand the fundamental biology of how COVID-19 spreads from the lungs into the body.

The research, in animal models, showed that during pregnancy flu spreads from the lungs through the blood vessels into the circulatory system, triggering a damaging hyperactive immune response.

Led by RMIT University in collaboration with researchers and clinicians from Ireland and Australia, the new study is published in the Proceedings of the National Academy of Sciences.

Lead author Dr Stella Liong said the research suggests the vascular system is at the heart of the potentially devastating complications

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